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Was ist Somatrogon?



Somatrogon (Natrium-Somatotropin) ist ein synthetisches Wachstumshormon, das zur Behandlung von Wachstumsstörungen bei Kindern und Erwachsenen verwendet wird. Es wird als Injektion verabreicht und ersetzt fehlendes körpereigenes Hormon.



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Anwendung




Indikation Dosierung Verabreichung


Kinder mit Wachstumshormonausfall 0,03 mg/kg Körpergewicht (max. 3 mg) Täglich oder alle zwei Tage, je nach Bedarf


Erwachsene mit Hypopituitarismus 0,2–1 mg/Tag Jeden zweiten Tag bis täglich


Körperliche Leistungssteigerung (Sport) 0,5–2 mg/Tag Unbefugt; nur unter ärztlicher Aufsicht






Die Injektion erfolgt intramuskulär oder subkutan.


Häufigkeit und Menge werden individuell angepasst.


Eine regelmäßige Blutuntersuchung zur Kontrolle von IGF-1-Spiegeln ist erforderlich.






Wirkungsweise



Somatrogon wirkt, indem es an das Wachstumshormonrezeptor (GHR) bindet. Dadurch wird die Produktion des Insulin-ähnlichen Wachstumsfaktors 1 (IGF-1) in der Leber angeregt. IGF-1 steuert Zellteilung und Proteinsynthese, was zu:





Gewichtszunahme durch Muskelaufbau


Knochenwachstum bei Kindern


Erhöhte Energie und Ausdauer






Nebenwirkungen




Typ Häufigkeit Beschreibung


Ödeme 10–20 % Schwellungen, besonders an Händen, Füßen und Gesicht.


Glukosestoffwechsel-Störungen

Bernd Saul, 19 years
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